The Schr\" odinger equations which are exactly solvable in terms of associated special functions are directly related to some self-adjoint operators defined in the theory of hypergeometric type equations. The fundamental formulae occurring in a supersymmetric approach to these Hamiltonians are consequences of some formulae concerning the general theory of associated special functions. We use this connection in order to obtain a general theory of Schr\" odinger equations exactly solvable in terms of associated special functions, and to extend certain results known in the case of some particular potentials.
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